Usage

Dissolve the powder in the entire 5% sodium bicarbonate and shake until a clear solution is obtained. Then add 0.9% sodium chloride to the vial

• 5 ml of 0.9% sodium chloride to obtain 6 ml of 10 mg / ml artesunate solution, for IV injection
• 2 ml of 0.9% sodium to obtain 3 ml of artesunate solution of 20 mg / ml, for IM injection

with a 1 ml ampoule of 5% sodium bicarbonate and a 5 ml ampoule of 0.9% sodium chloride, for slow IV injection (3 to 5 minutes) or slow IM. NU NCA MANAGE Perfusion IV .

Each vial contains:

• Artesunate (Sterile) 30mg

Indications

Used for acute attack and cerebral type of malaria.

Posology

Injectable artesunate is administered intravenously (IV) or intramuscularly (IM) for the treatment of severe malaria caused by P. falciparum.

The WHO strongly recommends the use of IV or IM artesunate in adults and children suffering from severe malaria (including infants, pregnant women in all trimesters, and lactating women) for at least 24 hours and until the patient can tolerate a full course of oral ACT therapy.

When using artesunate as an IM injection, give adults and children a single intramuscular dose of artesunate (as a pre-referral) and refer to an appropriate facility for further care.

Dosing Regimen

• Day 1 Dose 1: on admission (0 Hours)
• Day 1 Dose 2: 12 hours later
• Day 2 Dose 3: 24 hours after first dose