The treatment of fluid retention associated with heart failure, including left ventricular failure, cirrhosis of the liver and renal disease, including nephrotic syndrome.
The treatment of mild to moderate hypertension when brisk diuretic response is required. Alone or in combination with other anti-hypertensive agents in the treatment of more severe cases.
Posology
The initial adult dose is 40mg daily, reduced to 20mg daily or 40mg on alternative days. In some patients daily doses of 80mg or higher (given in divided doses) may be required.